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对贝沙罗汀凝胶有反应的亲毛囊性蕈样肉芽肿

Folliculotropic mycosis fungoides responding to bexarotene gel.

作者信息

Walling Hobart W, Swick Brian L, Gerami Pedram, Scupham Richard K

机构信息

Town Square Dermatology, Coralville, IA 52241, USA.

出版信息

J Drugs Dermatol. 2008 Feb;7(2):169-71.

Abstract

Folliculotropic mycosis fungoides (FMF) is an uncommon and potentially aggressive form of cutaneous T cell lymphoma (CTCL). Phototherapy, radiotherapy, and systemic chemotherapy are the most commonly employed treatment options, but may have limited success and common adverse reactions. Bexarotene gel is a topical retinoid X receptor (RXR) agonist with activity on the follicular unit that has not been previously reported in the management of FME The case of a 73-year-old male with FMF that responded to bexarotene gel is presented.

摘要

毛囊性蕈样肉芽肿(FMF)是一种罕见且具有潜在侵袭性的皮肤T细胞淋巴瘤(CTCL)。光疗、放疗和全身化疗是最常用的治疗选择,但可能效果有限且不良反应常见。贝沙罗汀凝胶是一种局部类视黄醇X受体(RXR)激动剂,对毛囊单位有活性,此前尚未见其用于FMF治疗的报道。本文报告了1例73岁男性FMF患者使用贝沙罗汀凝胶后有反应的病例。

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