Ueno M, Shinada K, Yanagisawa T, Mori C, Yokoyama S, Furukawa S, Takehara S, Kawaguchi Y
Department of Oral Health Promotion, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Oral Dis. 2008 Apr;14(3):264-9. doi: 10.1111/j.1601-0825.2007.01374.x.
The aim of this study was to evaluate the clinical ability of Breathtron by comparing it with other malodor measurement procedures: the organoleptic test (OT) and gas chromatography (GC).
Patients were 475 patients who visited a fresh breath clinic. Oral malodor was measured with the OT, GC, and Breathtron. Correlation analysis and two linear regression analyses were conducted to examine the relationship of the Breathtron values with OT scores and volatile sulfide compound (VSC) concentrations by GC: i.e. the regression of Breathtron on OT and the regression of Breathtron on total VSCs by GC. Receiver operating characteristics (ROC) analysis was conducted to investigate the sensitivity and specificity of Breathtron.
The Breathtron values were significantly correlated with OT and VSCs by GC. In the regression analysis, predicted Breathtron values were 199.3 and 520.1 ppb for OT scores 1 and 2, and reasonably close to total VSCs by GC between 550 and 750 ppb. The ROC analysis demonstrated that Breathtron is a useful and valuable adjunct measurement tool.
Breathtron is a simple, rapid and reliable appliance for screening oral malodor if an appropriate malodor threshold level is chosen.
本研究旨在通过将Breathtron与其他口臭测量方法(感官测试(OT)和气相色谱法(GC))进行比较,评估其临床应用能力。
研究对象为475名前往口气清新诊所就诊的患者。使用OT、GC和Breathtron测量口腔异味。进行相关性分析和两个线性回归分析,以检验Breathtron值与OT评分以及GC法测定的挥发性硫化物化合物(VSC)浓度之间的关系,即Breathtron对OT的回归以及Breathtron对GC法测定的总VSCs的回归。进行受试者工作特征(ROC)分析,以研究Breathtron的敏感性和特异性。
Breathtron值与OT和GC法测定的VSCs显著相关。在回归分析中,OT评分为1和2时,预测的Breathtron值分别为199.3和520.1 ppb,与GC法测定的总VSCs在550至750 ppb之间相当接近。ROC分析表明,Breathtron是一种有用且有价值的辅助测量工具。
如果选择合适的口臭阈值水平,Breathtron是一种用于筛查口腔异味的简单、快速且可靠的仪器。