van Venrooij Ger E P M, van Melick Harm H E, Eckhardt Mardy D, Boon Tom A
Department of Urology, University Medical Center, Utrecht, The Netherlands.
Urology. 2008 Mar;71(3):469-74. doi: 10.1016/j.urology.2007.11.033.
To investigate the information of voiding data in relation to symptoms and well-being in men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) and to compare this information with that of prostate volume (Vprostate), maximal free urinary flow rate (Q(max,free)), and obstruction grade (OG).
We performed mandatory tests, recommended tests, and pressure-flow studies in 384 consecutive men with LUTS suggestive of BPH. We estimated nocturia, diuria, and mean voided volume (Vmean) from their voiding diaries. Symptoms and well-being were quantified by American Urological Association symptom index (SI), quality-of-life score (QoL), symptom problem index (SPI), and BPH impact index (BII). We investigated the influence of Vprostate, Q(max,free), OG, Vmean, nocturia, and diuria on SI, QoL, SPI, and BII. We re-evaluated 48 men 6 months after transurethral resection of the prostate (TURP). We analyzed the predictive value of preoperative Q(max,free), Vprostate, OG, Vmean, nocturia, and diuria for the improvements of SI, QoL, SPI, and BII after TURP. We studied the improvements of Q(max,free), OG, Vmean, nocturia, and diuria after TURP and the improvements of SI, QoL, SPI, and BII.
Prostate volume, Q(max,free), and OG were only slightly associated with SI, QoL, SPI, and BII, in contrast to Vmean, nocturia, and diuria. The predictive value of all parameters on the outcome of TURP was poor. Improvements of all parameters were strongly associated with improvements of SI, QoL, SPI, and BII after TURP.
Voiding data should have a prominent role in the initial evaluation of men with LUTS suggestive of BPH.
研究提示良性前列腺增生（BPH）的下尿路症状（LUTS）男性患者的排尿数据与症状及健康状况之间的关系，并将此信息与前列腺体积（Vprostate）、最大自由尿流率（Q(max,free)）和梗阻分级（OG）进行比较。
我们对384例连续的提示BPH的LUTS男性患者进行了强制性检查、推荐检查和压力-流率研究。通过排尿日记估算夜尿、日间尿量和平均排尿量（Vmean）。症状和健康状况通过美国泌尿外科学会症状指数（SI）、生活质量评分（QoL）、症状问题指数（SPI）和BPH影响指数（BII）进行量化。我们研究了Vprostate、Q(max,free)、OG、Vmean、夜尿和日间尿量对SI、QoL、SPI和BII的影响。我们对48例接受经尿道前列腺切除术（TURP）6个月后的男性患者进行了重新评估。我们分析了术前Q(max,free)、Vprostate、OG、Vmean、夜尿和日间尿量对TURP后SI、QoL、SPI和BII改善情况的预测价值。我们研究了TURP后Q(max,free)、OG、Vmean、夜尿和日间尿量的改善情况以及SI、QoL、SPI和BII的改善情况。
与Vmean、夜尿和日间尿量相比，前列腺体积、Q(max,free)和OG与SI、QoL、SPI和BII仅存在轻微关联。所有参数对TURP结果的预测价值均较差。所有参数的改善与TURP后SI、QoL、SPI和BII的改善密切相关。
排尿数据在提示BPH的LUTS男性患者的初始评估中应发挥重要作用。
