人房水中的溶酶体酶活性。

Lysosomal enzyme activity in human aqueous humor.

作者信息

Weinreb R N, Jeng S, Miller A L

机构信息

Department of Ophthalmology, University of California, San Diego 92093.

出版信息

Clin Chim Acta. 1991 May 31;199(1):1-5. doi: 10.1016/0009-8981(91)90002-t.

DOI:10.1016/0009-8981(91)90002-t

PMID:1834372

Abstract

Activity of the lysosomal enzymes N-acetyl-beta-D-hexosaminidase, alpha-D-mannosidase, beta-D-glucuronidase, and beta-D-galactosidase was detected in aqueous humor from eyes undergoing intraocular surgery. There was no correlation between lysosomal enzyme activity and age. Lysosomal enzyme activity in human released by ocular tissues surrounding the anterior chamber including the cornea, trabecular meshwork, ciliary body, iris, and lens. Their release into aqueous humor may have a role in regulating aqueous outflow in normal and glaucomatous eyes.

摘要

在接受眼内手术的眼睛的房水中检测到了溶酶体酶N-乙酰-β-D-氨基己糖苷酶、α-D-甘露糖苷酶、β-D-葡糖醛酸糖苷酶和β-D-半乳糖苷酶的活性。溶酶体酶活性与年龄之间没有相关性。溶酶体酶活性由包括角膜、小梁网、睫状体、虹膜和晶状体在内的前房周围眼组织释放到人体中。它们释放到房水中可能在调节正常眼和青光眼眼中的房水流出方面发挥作用。