Fiedler K, Krüsmann G, Würfel W
Abeteilung für Sterilitätsdiagnostik und In-vitro-Fertilisation, Frauenklinik Dr. Krüsmann, München.
Geburtshilfe Frauenheilkd. 1991 Aug;51(8):643-8. doi: 10.1055/s-2007-1026415.
We report on our experience with surgical pelviscopy in the treatment of ectopic pregnancies after in-vitro fertilisation and, in comparison, during spontaneous cycles and during cycles with ovarian hyperstimulations and IUI. From 1.1. 1988 to 31.12.1990, 54 patients underwent this operation, 25 of these having undergone the IVF programme. All IVF patients had an extensive history of tubal sterility. Therefore, we found difficult anatomic conditions during the operation in most cases. Furthermore, the special conditions of the IVF treatment itself (e.g., multiple transfer of embryos into the uterus) caused a higher incidence of complicated situations (one triple ectopic, three ovarian ectopic pregnancies and one simultaneous pregnancy). Firstly, our experience leads to the conclusion, that surgical pelviscopy can be used for management of more complicate problems and can be regarded, so far, as an alternative to laparotomy. Secondly, laparotomy should not be replaced by pelviscopy in difficult situations (e.g., ovarian ectopics pregnancies). Surgical pelviscopy reduces the trauma of treatment, a consideration, which is very important especially for IVF patients. Because of the extraordinary problems related to ectopic pregnancies after IVF, we are at present sceptical about the use of other methods (e.g., instillation of prostaglandins or methotrexate) for these patients. Subsequently, 19 patients in the IVF group conceived with an intrauterine pregnancy after repeated IVF treatment. In the second group, 8 spontaneous intrauterine conceptions have occurred since.
我们报告了在体外受精后异位妊娠治疗中进行手术盆腔镜检查的经验,并与自然周期以及卵巢过度刺激和宫腔内人工授精周期中的情况进行了比较。从1988年1月1日至1990年12月31日,54例患者接受了该手术,其中25例接受了体外受精方案。所有体外受精患者都有广泛的输卵管不育病史。因此,我们发现大多数情况下手术中的解剖条件困难。此外,体外受精治疗本身的特殊情况(例如,多个胚胎移植到子宫内)导致复杂情况的发生率更高(1例三重重度异位妊娠、3例卵巢异位妊娠和1例同时妊娠)。首先,我们的经验得出结论,手术盆腔镜检查可用于处理更复杂的问题,并且到目前为止可被视为剖腹手术的替代方法。其次,在困难情况下(例如卵巢异位妊娠),剖腹手术不应被盆腔镜检查取代。手术盆腔镜检查减少了治疗创伤,这一考虑因素对体外受精患者尤为重要。由于与体外受精后异位妊娠相关的特殊问题,我们目前对这些患者使用其他方法(例如,前列腺素或甲氨蝶呤灌注)持怀疑态度。随后,体外受精组中的19例患者在重复体外受精治疗后宫内妊娠。在第二组中,自那时以来发生了8例自然宫内妊娠。