Araojo R, McCune S, Feibus K
Maternal Health Team, Pediatric and Maternal Health Staff, Office of New Drugs-Immediate Office, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Clin Pharmacol Ther. 2008 Apr;83(4):520-2. doi: 10.1038/clpt.2008.13.
In this issue, Gideon Koren and colleagues review the maternal and child health implications of drug-residue testing in maternal and neonatal hair and testing for drugs in meconium. Since the 1990s, these methods have been used to varying degrees in clinical practice, but recent technological advances have increased their accuracy and usability in the clinical setting. Compared with self-reported maternal use, drug-residue testing in hair and testing for drugs in meconium are more reliable methods for detecting drug and alcohol exposure during pregnancy. These methods can also provide insights into patterns of use and abuse of these substances.
在本期中,吉迪恩·科伦及其同事回顾了产妇和新生儿头发中的药物残留检测以及胎粪中药物检测对母婴健康的影响。自20世纪90年代以来,这些方法在临床实践中得到了不同程度的应用,但最近的技术进步提高了它们在临床环境中的准确性和可用性。与产妇自我报告的用药情况相比,头发中的药物残留检测和胎粪中药物检测是检测孕期药物和酒精暴露更可靠的方法。这些方法还可以深入了解这些物质的使用和滥用模式。