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[多发性颅内神经节胶质瘤。病例报告]

[Multiple intracranial ganglioglioma. Case report].

作者信息

Lakhdar F, Laghmari M, Gana R, Maaqili R, Bellakhdar F

机构信息

Service de neurochirurgie, hôpital Ibn-Sina, Rabat-Salé, Maroc.

出版信息

Neurochirurgie. 2008 Apr;54(2):97-100. doi: 10.1016/j.neuchi.2007.12.006. Epub 2008 Mar 19.

Abstract

Multiple intracranial ganglioglioma (GG) is an extremely rare condition, generally associated with van Recklinghausen neurofibromatosis. We report the case of a 26-year-old woman who presented with progressive tetraparesis, raised intracranial pressure and visual loss. The neuroradiologic workup demonstrated a multiple lesion involving the temporal lobe, the diencephalomesencephalon and the optical pathways. Computed tomography-guided stereotactic biopsy of a right temporal lesion led to the diagnosis of GG. In light of this case and the literature review, we discuss morphologic aspects, differential diagnosis and therapeutic options of GG. In patients with multiple cerebral tumors, search for multiple ganglioglioma is particularly important because of the therapeutic implications and the good prognosis of this tumor.

摘要

多发性颅内神经节胶质瘤(GG)是一种极为罕见的病症,通常与冯雷克林霍增氏神经纤维瘤病相关。我们报告了一例26岁女性病例,该患者出现进行性四肢轻瘫、颅内压升高和视力丧失。神经放射学检查显示多个病灶累及颞叶、间脑-中脑和视路。对右侧颞叶病灶进行计算机断层扫描引导下的立体定向活检,诊断为GG。结合该病例及文献复习,我们讨论了GG的形态学特征、鉴别诊断及治疗选择。在患有多发性脑肿瘤的患者中,由于该肿瘤的治疗意义及良好预后,查找多发性神经节胶质瘤尤为重要。

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