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用于磁共振成像的可控电场梯度线圈。

Controlled E-field gradient coils for MRI.

作者信息

Mansfield P, Haywood B

机构信息

Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham NG7 2RD, UK.

出版信息

Phys Med Biol. 2008 Apr 7;53(7):1811-27. doi: 10.1088/0031-9155/53/7/001. Epub 2008 Mar 10.

Abstract

Peripheral neural stimulation is a major problem in current gradient coil designs. Induced current problems in patients relate directly to gradient strength and modulation frequency. Present designs of gradient coil tend to limit ultra-high-speed imaging methods such as echo-planar imaging (EPI) and echo-volumar imaging (EVI) because of the effect of induced currents in the patient which produce neural stimulation resulting in tingling sensations and involuntary muscle twitch. Neural stimulation could also trigger epileptic fits and/or cardiac fibrillation. For reduction of induced currents, an important aspect is the coil geometry. It is desirable to design the gradient coil in such a way as to prevent closed loop circulating currents within the body. Preliminary results using a four-sector gradient coil with a rectangular geometry, operating in a low mutual coupling mode and using passive E-field control, indicate significant reduction of the E-field within the subject volume of the coil, leading to a reduction of induced currents in a patient. Such a reduction allows safer operation using higher magnetic gradient strengths together with faster scans. Currently very fast scans are prohibited by virtue of the neural stimulation effects produced in present standard coil geometries.

摘要

外周神经刺激是当前梯度线圈设计中的一个主要问题。患者体内的感应电流问题直接与梯度强度和调制频率相关。由于患者体内感应电流的影响会产生神经刺激,导致刺痛感和不自主肌肉抽搐,目前的梯度线圈设计往往会限制超高速成像方法,如回波平面成像(EPI)和回波容积成像(EVI)。神经刺激还可能引发癫痫发作和/或心脏纤颤。为了减少感应电流,一个重要方面是线圈几何形状。理想的做法是设计梯度线圈,以防止体内出现闭环循环电流。使用具有矩形几何形状、以低互耦模式运行并采用被动电场控制的四扇区梯度线圈的初步结果表明,线圈目标体积内的电场显著降低,从而减少了患者体内的感应电流。这种减少使得在使用更高磁梯度强度和更快扫描速度时能够更安全地操作。目前,由于现有标准线圈几何形状会产生神经刺激效应,非常快速的扫描是被禁止的。

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