Yan Guanghua, Liu Chihray, Lu Bo, Palta Jatinder R, Li Jonathan G
Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611, USA.
Phys Med Biol. 2008 Apr 21;53(8):2051-67. doi: 10.1088/0031-9155/53/8/004. Epub 2008 Mar 26.
The purpose of this study was to choose an appropriate head scatter source model for the fast and accurate independent planar dose calculation for intensity-modulated radiation therapy (IMRT) with MLC. The performance of three different head scatter source models regarding their ability to model head scatter and facilitate planar dose calculation was evaluated. A three-source model, a two-source model and a single-source model were compared in this study. In the planar dose calculation algorithm, in-air fluence distribution was derived from each of the head scatter source models while considering the combination of Jaw and MLC opening. Fluence perturbations due to tongue-and-groove effect, rounded leaf end and leaf transmission were taken into account explicitly. The dose distribution was calculated by convolving the in-air fluence distribution with an experimentally determined pencil-beam kernel. The results were compared with measurements using a diode array and passing rates with 2%/2 mm and 3%/3 mm criteria were reported. It was found that the two-source model achieved the best agreement on head scatter factor calculation. The three-source model and single-source model underestimated head scatter factors for certain symmetric rectangular fields and asymmetric fields, but similar good agreement could be achieved when monitor back scatter effect was incorporated explicitly. All the three source models resulted in comparable average passing rates (>97%) when the 3%/3 mm criterion was selected. The calculation with the single-source model and two-source model was slightly faster than the three-source model due to their simplicity.
本研究的目的是为基于多叶准直器(MLC)的调强放射治疗(IMRT)快速准确地进行独立平面剂量计算选择合适的头部散射源模型。评估了三种不同头部散射源模型在模拟头部散射和促进平面剂量计算方面的性能。本研究比较了三源模型、双源模型和单源模型。在平面剂量计算算法中,考虑到准直器和MLC开口的组合,从每个头部散射源模型导出空气中的注量分布。明确考虑了由于舌槽效应、叶片端部圆角和叶片透射引起的注量扰动。通过将空气中的注量分布与实验确定的笔形束核进行卷积来计算剂量分布。将结果与使用二极管阵列的测量结果进行比较,并报告符合2%/2 mm和3%/3 mm标准的通过率。结果发现,双源模型在头部散射因子计算方面达成了最佳一致性。对于某些对称矩形野和非对称野,三源模型和单源模型低估了头部散射因子,但当明确纳入监测器后向散射效应时,可以达成类似的良好一致性。当选择3%/3 mm标准时,所有三种源模型的平均通过率相当(>97%)。由于单源模型和双源模型计算简单,其计算速度比三源模型略快。