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[额叶皮质梗死与对侧姿势性及意向性震颤]

[Frontal cortical infarction and contralateral postural and international tremor].

作者信息

López Domínguez J M, Rojas-Marcos I, Sanz Fernández G, Robledo Strauss A

机构信息

Sección de Neurología, Hospital Juan Ramón Jiménez, Huelva, Spain.

出版信息

Neurologia. 2008 Jan-Feb;23(1):62-4.

Abstract

INTRODUCTION

Movement disorders, when caused by ischemic stroke, may appear as initial manifestation or after a variable interval of time. Among postictal movement disorders tremor is an uncommon manifestation. Holmes' tremor, which is a mixed tremor, is the most frequent type of tremor after stroke. It is associated to infarcts of various localizations like mesencephalon, pons, cerebellum, and thalamus. Cortical infarct is exceptional as a cause of tremor.

CASE REPORT

A sixty-three-year-old woman, with hypertension, who, 2 weeks after a cortical infarct located in the precentral circunvolution of the left frontal lobe, presented with a postural and intention tremor of low frequency (4 Hz) and high amplitude at the right arm. Tremor is still present 2 years after stroke and it has improved partially after treatment with clonazepam.

DISCUSSION

Frontal cortical infarcts may cause a contralateral postural and intentional tremor. It usually appears after a time interval. Tremor physiopathology may be related, in these cases, to interruption of the inhibitory fronto-subcortical motor circuit.

摘要

引言

缺血性卒中所致的运动障碍,可能在发病初期出现,也可能在一段可变的时间间隔后出现。在发作后运动障碍中,震颤是一种不常见的表现。霍姆斯震颤是一种混合性震颤,是卒中后最常见的震颤类型。它与中脑、脑桥、小脑和丘脑等不同部位的梗死有关。皮质梗死作为震颤的病因较为罕见。

病例报告

一名63岁患有高血压的女性,在左侧额叶中央前回发生皮质梗死后2周,出现右臂低频(4Hz)高幅度的姿势性和意向性震颤。卒中2年后震颤仍存在,使用氯硝西泮治疗后有所部分改善。

讨论

额叶皮质梗死可能导致对侧姿势性和意向性震颤。它通常在一段时间间隔后出现。在这些病例中,震颤的生理病理学可能与额叶-皮质下运动抑制回路的中断有关。

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