Frisk J, Carlhäll S, Källström A-C, Lindh-Astrand L, Malmström A, Hammar M
Division of Obstetrics and Gynaecology, Department of Molecular and Clinical Medicine, Faculty of Health Sciences, University Hospital of Linköping, Sweden.
Climacteric. 2008 Apr;11(2):166-74. doi: 10.1080/13697130801958709.
To evaluate the effects of electro-acupuncture (EA) and hormone therapy (HT) on vasomotor symptoms in women with a history of breast cancer.
Forty-five women were randomized to EA (n = 27) for 12 weeks or HT (n = 18) for 24 months. The number of and distress caused by hot flushes were registered daily before, during and up to 24 months after start of treatment.
In 19 women who completed 12 weeks of EA, the median number of hot flushes/24 h decreased from 9.6 (interquartile range (IQR) 6.6-9.9) at baseline to 4.3 (IQR 1.0-7.1) at 12 weeks of treatment (p < 0.001). At 12 months after start of treatment, 14 women with only the initial 12 weeks of EA had a median number of flushes/24 h of 4.9 (IQR 1.8-7.3), and at 24 months seven women with no other treatment than EA had 2.1 (IQR 1.6-2.8) flushes/24 h. Another five women had a decreased number of flushes after having additional EA. The 18 women with HT had a baseline median number of flushes/24 h of 6.6 (IQR 4.0-8.9), and 0.0 (IQR 0.0-1.6; p = 0.001) at 12 weeks.
Electro-acupuncture is a possible treatment of vasomotor symptoms for women with breast cancer and should be further studied for this group of women.
评估电针（EA）和激素疗法（HT）对有乳腺癌病史女性血管舒缩症状的影响。
45名女性被随机分为接受12周电针治疗组（n = 27）或24个月激素疗法组（n = 18）。在治疗开始前、治疗期间及治疗开始后长达24个月的时间里，每天记录潮热的次数及潮热引起的困扰程度。
19名完成12周电针治疗的女性，潮热的中位数/24小时从基线时的9.6（四分位数间距（IQR）6.6 - 9.9）降至治疗12周时的4.3（IQR 1.0 - 7.1）（p < 0.001）。在治疗开始后12个月，仅接受最初12周电针治疗的14名女性潮热的中位数/24小时为4.9（IQR 1.8 - 7.3），在24个月时，仅接受电针治疗的7名女性潮热次数为2.1（IQR 1.6 - 2.8）次/24小时。另外5名女性在接受额外的电针治疗后潮热次数减少。18名接受激素疗法的女性基线时潮热的中位数/24小时为6.6（IQR 4.0 - 8.9），在12周时为0.0（IQR 0.0 - 1.6；p = 0.001）。
电针是治疗乳腺癌女性血管舒缩症状的一种可能疗法，应对该组女性进行进一步研究。
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