Hu Wen-sheng, Zhang Zhi-fen
Department of Obstetrics, Affiliated Obstetric and Gynecology Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, China.
Zhonghua Fu Chan Ke Za Zhi. 2008 Jan;43(1):29-31.
To study the clinical characteristics of acute asthma during pregnancy, focusing on management of pregnant women presenting with an acute exacerbation.
A prospective observational study was conducted in 30 cases of acute exacerbations during pregnancy.
The prognosis of 25 patients with mild or moderate asthma was good for both mother and fetus; none had severe complications. Among 5 women who had severe exacerbations, there were 4 pulmonary co-infections, 1 with respiratory acidosis, 1 with respiratory acidosis plus metabolic alkalosis, and 4 with fetal growth-restriction.
This study highlights that pregnancy can worsen asthma control in some women. Effective management and prevention of asthma exacerbations during pregnancy is key to ensuring the safety of the mother and the fetus.
研究妊娠期急性哮喘的临床特征，重点关注急性加重期孕妇的管理。
对30例妊娠期急性加重患者进行前瞻性观察研究。
25例轻度或中度哮喘患者母婴预后良好；均无严重并发症。5例重度加重患者中，4例合并肺部感染，1例发生呼吸性酸中毒，1例合并呼吸性酸中毒加代谢性碱中毒，4例出现胎儿生长受限。
本研究强调妊娠可使部分女性哮喘控制恶化。妊娠期有效管理和预防哮喘加重是确保母婴安全的关键。
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