Vorob'ev Vladimir N, Anisimov Alexander V, Dautova Nailya R
Kazan Institute of Biochemistry and Biophysics, P.O.B. 30, 420111, Kazan, Russia.
Eur Biophys J. 2008 Jul;37(6):975-8. doi: 10.1007/s00249-008-0316-x. Epub 2008 Mar 27.
The translational displacement of the cytoplasmic water in Elodea stem cells resulting from protein motor activity was measured using the NMR method. A 24-h treatment with vincristine results in a reduction of the translational displacement of the cytoplasmic water. With a constant cytoplasmic streaming velocity, the dynamics of the translational displacement of the cytoplasmic water under the effect of taxol are characterized by a continuous increase at a concentration of 0.05 mM, and reaching a plateau at a concentration of 0.5 mM.
利用核磁共振方法测量了蛋白马达活性导致的伊乐藻茎细胞中细胞质水的平移位移。用长春新碱处理24小时会导致细胞质水平移位移减少。在细胞质流动速度恒定的情况下,紫杉醇作用下细胞质水平移位移的动力学特征是在浓度为0.05 mM时持续增加,在浓度为0.5 mM时达到平稳状态。