Sharov Alexei A, Ko Minoru S H
Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, Baltimore, MD 21224, USA.
Cell Stem Cell. 2007 Sep 13;1(3):237-8. doi: 10.1016/j.stem.2007.08.015.
In this issue of Cell Stem Cell, Pan et al. (2007) and Zhao et al. (2007) report genome-wide histone H3 trimethylations at lysines 4 and 27 in human embryonic stem (ES) cells. Similar gene sets arise via different experimental systems, advancing our understanding of stem cell epigenetics.
在本期《细胞·干细胞》杂志中,潘等人(2007年)和赵等人(2007年)报道了人类胚胎干细胞中赖氨酸4和27处全基因组范围的组蛋白H3三甲基化情况。相似的基因集通过不同的实验系统产生,这增进了我们对干细胞表观遗传学的理解。