Capelle L, Krawitz H
Department of Radiation Oncology, Auckland City Hospital, Auckland, New Zealand.
J Med Imaging Radiat Oncol. 2008 Feb;52(1):85-90. doi: 10.1111/j.1440-1673.2007.01919.x.
Esthesioneuroblastoma is a rare malignancy arising from the olfactory epithelium. We present a case history of a 75-year-old man who presented with a Kadish stage C esthesioneuroblastoma and underwent craniofacial surgery and adjuvant radiotherapy. Two years later he was found to have diffuse subdural deposits with distant bone and nodal metastases, treated with further radiotherapy. The patient's condition subsequently deteriorated and he died. Given this unusual pattern of failure, we review the recent published studies regarding the natural history, treatment and outcome for this tumour.
嗅神经母细胞瘤是一种起源于嗅上皮的罕见恶性肿瘤。我们报告一例75岁男性患者的病史,该患者患有卡迪什C期嗅神经母细胞瘤,接受了颅面外科手术和辅助放疗。两年后,发现他有弥漫性硬膜下沉积物以及远处骨和淋巴结转移,遂接受进一步放疗。患者病情随后恶化并死亡。鉴于这种不寻常的复发模式,我们回顾了最近发表的关于该肿瘤自然史、治疗和预后的研究。