Weber Andreas, Roesch Thomas, Pointner Sebastian, Born Peter, Neu Bruno, Meining Alexander, Schmid Roland M, Prinz Christian
Department of Internal Medicine II, Technical University of Munich, Munich, Germany.
Pancreas. 2008 Mar;36(2):187-91. doi: 10.1097/MPA.0b013e31815ac54c.
Obstruction of the biliary tract can lead to severe complications. The common treatment of patients with biliary tract obstruction is the decompression by endoscopic procedures. However, cannulation of the common bile duct can be difficult under certain instances because of anatomical variations or obstruction at the biliary entrance level. Needle-knife or precut sphincterotomy has been described as technique to facilitate biliary access in patients with difficult bile duct cannulation. In the current study, we evaluated success and complication rates of a wire-guided transpancreatic precut technique at our hospital.
Between January 2003 and June 2006, a total of 108 patients with jaundice but with inaccessible bile ducts using classic techniques (failed primary cannulation or failed needle-knife papillotomy) underwent a wire-guided transpancreatic precut sphincterotomy. Precuts were performed using a soft guide wire placed in the pancreatic duct without injection of contrast fluid into the pancreatic duct.
We studied cannulation success and complications associated with postprocedural hospitalization. Bile duct cannulation was successful in 103 (95.4%) of the 108 patients. Five patients (4.6%) required a percutaneous transhepatic biliary drainage. In 108 patients, there were 12 patients (11.1%) with procedure-related complications including acute pancreatitis (n = 6) and bleeding (n=6). Four patients had a mild and transient pancreatitis (pain improvement after 2 days), 2 had severe pancreatitis that was reversible after 7 days of conservative treatment. In 4 cases, a blood transfusion (each with 2 erythrocyte concentrates) became necessary. Perforations and other severe procedure-related deaths did not occur.
Transpancreatic precut sphincterotomy using a soft guide wire is a safe and effective procedure in patients with difficult bile duct access where classic sphincterotomy or needle-knife procedures fail.
胆道梗阻可导致严重并发症。胆道梗阻患者的常见治疗方法是通过内镜手术进行减压。然而,由于解剖变异或胆道入口水平的梗阻,在某些情况下,胆总管插管可能会很困难。针刀或预切开括约肌切开术已被描述为促进胆管插管困难患者胆道通路的技术。在本研究中,我们评估了我院采用导丝引导的经胰预切开技术的成功率和并发症发生率。
在2003年1月至2006年6月期间,共有108例黄疸患者,采用经典技术无法进入胆管(初次插管失败或针刀乳头切开术失败),接受了导丝引导的经胰预切开括约肌切开术。预切开是通过将一根软导丝放置在胰管内进行的,而不向胰管内注射造影剂。
我们研究了插管成功率和与术后住院相关的并发症。108例患者中有103例(95.4%)胆管插管成功。5例患者(4.6%)需要经皮经肝胆道引流。108例患者中,有12例(11.1%)出现与手术相关的并发症,包括急性胰腺炎(n = 6)和出血(n = 6)。4例患者发生轻度短暂性胰腺炎(2天后疼痛改善),2例患者发生严重胰腺炎,经7天保守治疗后可逆。4例患者需要输血(每例输注2单位红细胞浓缩液)。未发生穿孔和其他严重的与手术相关的死亡。
对于经典括约肌切开术或针刀手术失败的胆管通路困难患者,使用软导丝进行经胰预切开括约肌切开术是一种安全有效的手术方法。