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96岁重度主动脉瓣狭窄患者的电休克治疗:病例报告及文献综述

Electroconvulsive therapy in a 96-year-old patient with severe aortic stenosis: a case report and review of the literature.

作者信息

O'Reardon John P, Cristancho Mario A, Cristancho Pilar, Fontecha Jeisson F, Weiss David

机构信息

ECT Service, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

出版信息

J ECT. 2008 Mar;24(1):96-8. doi: 10.1097/YCT.0b013e31814da9d5.

Abstract

We report the safe administration of a course of electroconvulsive therapy (ECT) in a 96-year-old woman with severe aortic stenosis. The patient experienced a relapse of her severe depression when ECT had been withheld because of increased concerns regarding medical risk given her age and degree of aortic stenosis. Reassessment of the case confirmed severe stenosis with a valve area of 0.5 cm2 and a peak pressure gradient across the valve of 110 mm Hg. The ventricular ejection was normal at 70% however, and after a careful weighing of the risk of ECT treatment versus the risk of withholding ECT, it was decided to proceed with ECT in this case. In the event, ECT was very well tolerated by the patient, and she experienced a full remission of symptoms. She continues to receive maintenance ECT successfully at a once-per-month frequency. This case illustrates that neither age nor aortic stenosis by itself precludes ECT in the setting of severe depression. Rather, in each case, a careful weighing of the risks both of proceeding with and withholding ECT is warranted.

摘要

我们报告了对一名患有严重主动脉瓣狭窄的96岁女性进行一个疗程的电休克治疗(ECT)的安全管理情况。由于考虑到患者年龄和主动脉瓣狭窄程度,医疗风险增加,此前停用ECT时,该患者的重度抑郁症复发。对病例的重新评估证实存在严重狭窄,瓣膜面积为0.5平方厘米,瓣膜两端的峰值压力梯度为110毫米汞柱。然而,心室射血正常,为70%,在仔细权衡ECT治疗风险与停用ECT的风险后,决定对该病例进行ECT治疗。结果,患者对ECT耐受性良好,症状完全缓解。她继续每月成功接受一次维持性ECT治疗。该病例表明,在重度抑郁症的情况下,年龄和主动脉瓣狭窄本身都不排除ECT治疗。相反,在每种情况下,都有必要仔细权衡进行ECT和停用ECT的风险。

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