Shrivastava Vivek, Tariq Omar, Tiam ReeNee, Nyhsen Christiane, Marsh Ralph
Department of Radiology, Freeman Hospital, Freeman Road, Newcastle Upon Tyne, NE7 7DN, UK.
Cardiovasc Intervent Radiol. 2008 Sep-Oct;31(5):931-6. doi: 10.1007/s00270-008-9328-2. Epub 2008 Apr 1.
To evaluate the efficacy, risks, and survival after palliative colorectal stenting at a single center, we conducted a retrospective review of consecutive patients who had colorectal self-expanding metal stents (SEMSs) inserted over an 8-year period (September 1998 to September 2006) to relieve an obstructing colorectal tumor. All patients either had proven distant metastases or were unfit for surgical decompression. A single interventional radiologist (R.M.) inserted the stents, which were either Memotherm or WallFlex. Ninety-one patients with a median age of 73 years had a colorectal stent inserted for palliation of an obstructing colorectal malignancy. Technical success was achieved in 81 of 91 (89%) patients, and clinical success in 80 of 81 (99%). At the time of analysis (December 2006), 13 of 91 (14.2%) patients were alive. The patients who died had a median survival of 59 days, IQR 17-181 days. Seven (7/81) patients suffered stent migration, which occurred 10.3 days (IQR, 5-14 days) after the procedure. Three patients (3/81) re-presented with intestinal obstruction secondary to tumor ingrowth and 10 (10.9%) patients suffered bowel perforation. Ten patients (10.9%) had two stents inserted coaxially and overlapping in one procedure. This was performed in cases where the stricture was too long to be easily crossed by a single stent. We conclude that colorectal SEMS is a safe and effective mode of treatment for the palliation of obstructing colorectal cancers, which avoids high-risk surgery.
为评估在单一中心进行姑息性结直肠支架置入术后的疗效、风险和生存率,我们对在8年期间(1998年9月至2006年9月)因结直肠肿瘤梗阻而置入结直肠自膨式金属支架(SEMS)的连续患者进行了回顾性研究。所有患者均已证实有远处转移或不适合手术减压。由一名介入放射科医生(R.M.)置入支架,支架类型为Memotherm或WallFlex。91例中位年龄为73岁的患者因结直肠恶性肿瘤梗阻而置入结直肠支架以缓解症状。91例患者中有81例(89%)技术成功,81例技术成功的患者中有80例(99%)临床成功。在分析时(2006年12月),91例患者中有13例(14.2%)存活。死亡患者的中位生存期为59天,四分位间距为17 - 181天。7例(7/81)患者发生支架移位,发生在术后10.3天(四分位间距,5 - 14天)。3例患者(3/81)因肿瘤长入导致肠梗阻复发,10例患者(10.9%)发生肠穿孔。10例患者(10.9%)在一次操作中同轴重叠置入了两个支架。在狭窄过长难以被单个支架轻松跨越的情况下进行了此项操作。我们得出结论,结直肠SEMS是缓解结直肠癌梗阻的一种安全有效的治疗方式,可避免高风险手术。