Berry Jay G, Hall Matthew A, Sharma Vidya, Goumnerova Liliana, Slonim Anthony D, Shah Samir S
Department of Medicine, Complex Care Service, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA.
Neurosurgery. 2008 Feb;62(2):445-53; discussion 453-4. doi: 10.1227/01.neu.0000316012.20797.04.
To evaluate risk factors and predictors of cerebrospinal ventricular shunt revisions in children.
A retrospective, longitudinal cohort of 1307 children ages 0 to 18 years undergoing initial ventricular shunt placement in the year 2000, with follow-up through 2005, from 32 freestanding children's hospitals within the Pediatric Health Information Systems database was studied. Rates of ventricular shunt revision were compared with patient demographic, clinical, and hospital characteristics with use of bivariate and multivariate regression accounting for hospital clustering.
Thirty-seven percent of children required at least one shunt revision within 5 years of initial shunt placement; 20% of children required two or more revisions. Institutional rates of first shunt revision ranged from 20 to 70% of initial shunts placed among the 32 hospitals in the cohort. Hospitals where one to 20 initial shunt placements per year experienced the highest initial shunt revision rate (42%). Hospitals performing over 83 initial shunt placements per year experienced the lowest revision rate (22%). We found that children undergoing shunt placement in the Midwest were more likely to experience multiple shunt revisions (odds ratio, 1.25; 95% confidence interval, 1.06-1.47) after controlling for hospital volume, shunt type, age, and diagnosis associated with initial shunt placement.
Higher hospital volume of initial shunt placement was associated with lower revision rates. Substantial hospital variation in the rates of ventricular shunt revision exists among children's hospitals. Future prospective studies are needed to examine the reasons for the variability in shunt revision rates among hospitals, including differences in specific processes of care.
评估儿童脑脊液脑室分流术翻修的危险因素及预测因素。
对2000年在小儿健康信息系统数据库中32家独立儿童医院接受初次脑室分流术的1307名0至18岁儿童进行回顾性纵向队列研究,随访至2005年。采用双变量和多变量回归分析并考虑医院聚类情况,将脑室分流术翻修率与患者人口统计学、临床和医院特征进行比较。
37%的儿童在初次分流术后5年内至少需要进行一次分流术翻修;20%的儿童需要进行两次或更多次翻修。在队列中的32家医院中,初次分流术翻修的机构率在初次分流术的20%至70%之间。每年进行1至20例初次分流术的医院初次分流术翻修率最高(42%)。每年进行超过83例初次分流术的医院翻修率最低(22%)。我们发现,在控制医院手术量、分流类型、年龄以及与初次分流术相关的诊断后,在美国中西部接受分流术的儿童更有可能经历多次分流术翻修(优势比为1.25;95%置信区间为1.06 - 1.47)。
初次分流术的医院手术量越高,翻修率越低。儿童医院之间脑室分流术翻修率存在显著差异。未来需要进行前瞻性研究,以探讨医院之间分流术翻修率差异的原因,包括具体护理过程的差异。