Kavak A, Yeşildal N, Parlak A H, Gökdemir G, Aydoğan I, Anul H, Baykal C
Department of Dermatology, Düzce Medical School, Düzce University, Düzce, Turkey.
J Eur Acad Dermatol Venereol. 2008 Aug;22(8):977-81. doi: 10.1111/j.1468-3083.2008.02699.x. Epub 2008 Apr 1.
Alopecia areata is a complex genetic disease with still many unknown aspects, and many studies have been tried to find some clues about it.
We aimed to investigate the demographic and clinical characteristics of alopecia areata in Turkish patients.
Demographic data, localization, attack number in addition to some parameters such as disease duration, severity, age of onset, family history and ophiasis pattern were evaluated in 539 alopecia areata patients.
The male to female ratio was 1.6:1. Occipital and beard-moustache areas were mostly affected. Positive family history was noticed in 24.1% of the patients. The age of onset was earlier in women than in men (P = 0.04). Severe forms showed more persistent (> or = 1 year) disease duration (P = 0.00). Ophiasis was more common in severe, long duration (> or = 1 year) and early onset (< or = 18 years) disease (P = 0.00 for all parameters). Childhood alopecia areata (< or = 18 years) was also associated with long duration of the disease (P = 0.016) and positive family history (P = 0.008) when compared with adult onset (> 18 years) alopecia areata.
斑秃是一种复杂的遗传性疾病,仍有许多未知方面,许多研究试图寻找有关它的一些线索。
我们旨在调查土耳其患者斑秃的人口统计学和临床特征。
对539例斑秃患者的人口统计学数据、病变部位、发作次数以及病程、严重程度、发病年龄、家族史和匐行性斑秃模式等一些参数进行了评估。
男女比例为1.6:1。枕部和胡须区域最常受累。24.1%的患者有阳性家族史。女性的发病年龄早于男性(P = 0.04)。严重形式的病程更持久(≥1年)(P = 0.00)。匐行性斑秃在严重、病程长(≥1年)和发病早(≤18岁)的疾病中更常见(所有参数P = 0.00)。与成人发病(>18岁)的斑秃相比,儿童期斑秃(≤18岁)也与病程长(P = 0.016)和阳性家族史(P = 0.008)相关。