Ordorica Raul, Rodriguez Alejandro R, Coste-Delvecchio Fernando, Hoffman Mitchell, Lockhart Jorge
Division of Urology, University of South Florida, Tampa, FL 33612-9497, USA.
BJU Int. 2008 Aug;102(3):333-6. doi: 10.1111/j.1464-410X.2008.07608.x. Epub 2008 Apr 2.
To report an increase in the referral of patients with disabling complications after the failure of conservative therapy, their presentation, final surgical management and clinical outcome, following the use of non-autologous slings (NAS), currently the primary surgical procedure for managing stress urinary incontinence (SUI) in women.
Thirty-eight patients (mean age 64 years) required surgical management for disabling complications after placing a NAS for SUI. Sling types were synthetic (25), xenografts (six) and allografts (four). Twenty (53%) patients presented with bladder outlet obstruction, 13 (34%) with sling erosion, three (8%) with worsened SUI, and two (5%) with unobstructive severe urgency and frequency.
The sling was dissected and incised with no complication in 19 of 20 patients. One had a posterior urethral defect during sling dissection. Twelve patients (60%) acquired normal voiding and were continent. Among the 13 patients who had the sling dismantled and urethrolysis, two had recurrent or persistent SUI, two de-novo urgency/frequency and one developed osteitis pubis. Three patients with disabling SUI received a pubovaginal sling placed proximal to the bladder neck, and had an overall improvement in their urinary control with no retention. Two unobstructed patients with urgency and frequency did not improve with anticholinergic medication and pelvic floor therapy, and are now candidates for botulinum toxin injection or neurostimulation.
The complication rate with periurethral NAS for managing SUI in females is substantial. Patients with refractory urgency/frequency after the sling need a complete evaluation with cystoscopy and video-urodynamics. Obstruction and erosion are the commonest problems and require surgical correction.
报告在使用非自体吊带(NAS)后,保守治疗失败的患者出现致残性并发症的转诊增加情况、其表现、最终手术管理及临床结果。NAS目前是治疗女性压力性尿失禁(SUI)的主要手术方法。
38例患者(平均年龄64岁)在因SUI放置NAS后出现致残性并发症而需要手术治疗。吊带类型包括合成材料(25例)、异种移植物(6例)和同种异体移植物(4例)。20例(53%)患者出现膀胱出口梗阻,13例(34%)出现吊带侵蚀,3例(8%)SUI加重,2例(5%)出现无梗阻性严重尿急和尿频。
20例患者中有19例在吊带解剖和切开时未出现并发症。1例在吊带解剖时出现后尿道缺损。12例患者(60%)排尿恢复正常且控尿良好。在13例拆除吊带并行尿道松解术的患者中,2例出现复发性或持续性SUI,2例新发尿急/尿频,1例发生耻骨炎。3例致残性SUI患者在膀胱颈近端放置了耻骨后阴道吊带,尿控能力总体改善且无尿潴留。2例无梗阻性尿急和尿频患者使用抗胆碱能药物和盆底治疗后未改善,目前是肉毒毒素注射或神经刺激的候选对象。
女性使用尿道周围NAS治疗SUI的并发症发生率较高。吊带术后出现难治性尿急/尿频的患者需要进行膀胱镜检查和影像尿动力学的全面评估。梗阻和侵蚀是最常见的问题,需要手术矫正。