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Somatostatin receptor subtype 4 couples to the M-current to regulate seizures.
J Neurosci. 2008 Apr 2;28(14):3567-76. doi: 10.1523/JNEUROSCI.4679-07.2008.
2
Functional effects of somatostatin receptor 1 activation on synaptic transmission in the mouse hippocampus.
J Neurochem. 2009 Dec;111(6):1466-77. doi: 10.1111/j.1471-4159.2009.06423.x. Epub 2009 Oct 7.
3
Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy.
Epilepsia. 2009 Apr;50(4):629-45. doi: 10.1111/j.1528-1167.2008.01725.x. Epub 2008 Jul 24.
4
Somatostatin increases a voltage-insensitive K+ conductance in rat CA1 hippocampal neurons.
J Neurophysiol. 1998 Mar;79(3):1230-8. doi: 10.1152/jn.1998.79.3.1230.
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The sleep-modulating peptide cortistatin augments the h-current in hippocampal neurons.
J Neurosci. 2003 Nov 26;23(34):10884-91. doi: 10.1523/JNEUROSCI.23-34-10884.2003.
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Somatostatin: an endogenous antiepileptic.
Mol Cell Endocrinol. 2008 May 14;286(1-2):96-103. doi: 10.1016/j.mce.2007.12.004. Epub 2007 Dec 14.
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Striatal potassium channel dysfunction in Huntington's disease transgenic mice.
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Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons.
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Glutamate transporters regulate extrasynaptic NMDA receptor modulation of Kv2.1 potassium channels.
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The Primary Cilia are Associated with the Axon Initial Segment in Neurons.
Adv Sci (Weinh). 2025 Mar;12(9):e2407405. doi: 10.1002/advs.202407405. Epub 2025 Jan 13.
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Somatostatin: Linking Cognition and Alzheimer Disease to Therapeutic Targeting.
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Elucidation of the binding mode of organic polysulfides on the human TRPA1 receptor.
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Somatostatin, a Presynaptic Modulator of Glutamatergic Signal in the Central Nervous System.
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本文引用的文献

1
K+ M-current regulates the transition to seizures in immature and adult hippocampus.
Epilepsia. 2007 Nov;48(11):2047-58. doi: 10.1111/j.1528-1167.2007.01193.x. Epub 2007 Jul 25.
2
Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures.
Neurology. 2007 Apr 10;68(15):1197-204. doi: 10.1212/01.wnl.0000259034.45049.00.
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Regulation of KCNQ channels by manipulation of phosphoinositides.
J Physiol. 2007 Aug 1;582(Pt 3):911-6. doi: 10.1113/jphysiol.2007.132647. Epub 2007 Apr 5.
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Retigabine.
Neurotherapeutics. 2007 Jan;4(1):149-54. doi: 10.1016/j.nurt.2006.11.012.
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Imaging the neural substrates involved in the genesis of pentylenetetrazol-induced seizures.
Epilepsia. 2006 Apr;47(4):745-54. doi: 10.1111/j.1528-1167.2006.00502.x.
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Pathways modulating neural KCNQ/M (Kv7) potassium channels.
Nat Rev Neurosci. 2005 Nov;6(11):850-62. doi: 10.1038/nrn1785.
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Mechanisms of somatostatin-evoked responses in neurons of the rat lateral amygdala.
Eur J Neurosci. 2005 Feb;21(3):755-62. doi: 10.1111/j.1460-9568.2005.03922.x.
10
Somatostatin receptors differentially affect spontaneous epileptiform activity in mouse hippocampal slices.
Eur J Neurosci. 2004 Nov;20(10):2711-21. doi: 10.1111/j.1460-9568.2004.03741.x.

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