Zempsky William T, Loiselle Kristin A, McKay Kathleen, Blake Gabriella L, Hagstrom J Nathan, Schechter Neil L, Kain Zeev N
Connecticut Children's Medical Center, Hartford, Connecticut 06106, USA.
Pediatr Blood Cancer. 2008 Aug;51(2):265-8. doi: 10.1002/pbc.21572.
This study was conducted to assess the care of pediatric patients hospitalized for sickle cell disease-related vasoocclusive episodes (VOE). The aim of this research was to illustrate the course of pain scores and methods of therapeutic intervention during hospitalization.
Retrospective medical chart reviews were conducted to collect pain assessment and management data about children hospitalized during a 2-year period at an urban children's hospital. T tests and Chi-square analyses were used to identify differences in demographic variables, pain scores and opiate utilization.
There were 59 children with 134 hospitalizations for VOE in a 2-year period. 50.8% of the patients were male; the mean age was 11.5 +/- 4.9 years. The average length of hospitalization was 4.6 +/- 2.7 days (range 1-19 days). Older patients stayed in the hospital significantly longer than younger patients (P = 0.002). Pain scores remained in the moderate to severe range (> or =5 out of 10) for many days in the majority of patients. Results failed to reveal significant differences in pain scores and opiate utilization between patients who had short versus extended hospitalizations, and for those patients with frequent versus infrequent hospitalizations for pain.
Despite opiate dosing within recommended guidelines, mean pain scores remain in the moderate to severe range for several days following hospitalization for VOE. Future research should explore the factors which influence pain scores, as well as improved pain assessment and management techniques.
本研究旨在评估因镰状细胞病相关血管闭塞性发作(VOE)住院的儿科患者的护理情况。本研究的目的是阐明住院期间疼痛评分的变化过程以及治疗干预方法。
进行回顾性病历审查,以收集一家城市儿童医院在两年期间住院儿童的疼痛评估和管理数据。采用t检验和卡方分析来确定人口统计学变量、疼痛评分和阿片类药物使用情况的差异。
在两年期间,有59名儿童因VOE住院134次。50.8%的患者为男性;平均年龄为11.5±4.9岁。平均住院时间为4.6±2.7天(范围为1 - 19天)。年龄较大的患者住院时间明显长于年龄较小的患者(P = 0.002)。大多数患者的疼痛评分在许多天内都保持在中度至重度范围内(10分制中≥5分)。结果未能显示短期住院与长期住院患者之间以及疼痛发作频繁与不频繁患者之间在疼痛评分和阿片类药物使用上有显著差异。
尽管阿片类药物的剂量在推荐指南范围内,但VOE住院后数天内平均疼痛评分仍保持在中度至重度范围内。未来的研究应探索影响疼痛评分的因素,以及改进疼痛评估和管理技术。