Panagiotakos Demosthenes B, Pitsavos Christos, Chrysohoou Christine, Stefanadis Christodoulos
Department of Dietetics-Nutrition, Harokopio University, Greece.
Angiology. 2008 Apr-May;59(2):156-65. doi: 10.1177/0003319707304576. Epub 2008 Apr 2.
During 2000 to 2002, 700 men (59 +/- 10 years) and 148 women (65 +/- 9 years) patients with first event of an ACS were randomly selected from cardiology clinics of Greek regions. Afterwards, 1078 population-based, age-matched and sex-matched controls were randomly selected from the same hospitals. The frequency ratio between men and women in the case series of patients was about 4:1, in both south and north Greek areas. Hierarchical classification analysis showed that for north Greek areas family history of coronary heart disease, hypercholesterolemia, hypertension, diabetes (explained variability 35%), and less significantly, dietary habits, smoking, body mass index, and physical activity status (explained variability 4%) were associated with the development of ACS, whereas for south Greek areas hypercholesterolemia, family history of coronary heart disease, diabetes, smoking, hypertension, dietary habits, physical activity (explained variability 34%), and less significantly body mass index (explained variability <1%), were associated with the development of the disease.
在2000年至2002年期间，从希腊各地区的心脏病诊所中随机选取了700名男性（59±10岁）和148名女性（65±9岁）首次发生急性冠状动脉综合征（ACS）的患者。之后，从同一些医院中随机选取了1078名基于人群、年龄和性别匹配的对照。在希腊南部和北部地区，患者病例系列中男性与女性的频率比均约为4:1。分层分类分析表明，对于希腊北部地区，冠心病家族史、高胆固醇血症、高血压、糖尿病（可解释变异性35%），以及不太显著的饮食习惯、吸烟、体重指数和身体活动状况（可解释变异性4%）与ACS的发生有关；而对于希腊南部地区，高胆固醇血症、冠心病家族史、糖尿病、吸烟、高血压、饮食习惯、身体活动（可解释变异性34%），以及不太显著的体重指数（可解释变异性<1%）与该病的发生有关。
