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应对化疗引起的过早绝经。

"Coming to grips" with chemotherapy-induced premature menopause.

作者信息

Knobf M Tish

机构信息

School of Nursing, Yale University, New Haven, Connecticut 06536-0740, USA.

出版信息

Health Care Women Int. 2008 Apr;29(4):384-99. doi: 10.1080/07399330701876562.

Abstract

Chemotherapy for early stage breast cancer has significantly improved survival outcomes but is associated with ovarian toxicity, resulting in early menopause for many premenopausal women. A qualitative study was conducted that generated a grounded theory explaining how women carried on with life in response to breast cancer and menopause. My purpose in this article is to describe three distinct types of responses from women in that study: making the best of it, struggling and barely noticing. The degree of menopausal symptom distress and perceived level of preparation for the menopause experience had the greatest influence on the type of response.

摘要

早期乳腺癌的化疗显著改善了生存结果,但与卵巢毒性相关,导致许多绝经前女性提前绝经。一项定性研究生成了一个扎根理论,解释了女性如何应对乳腺癌和绝经并继续生活。我在本文中的目的是描述该研究中女性的三种不同反应类型:尽力而为、挣扎和几乎未察觉。绝经症状困扰的程度和对绝经经历的感知准备水平对反应类型的影响最大。

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