Palumbo Emilio
Recenti Prog Med. 2008 Jan;99(1):39-41.
Sydenham's chorea, the neurological manifestation of rheumatic fever, is the most common acquired chorea of childhood. This disorder is secondary to an autoimmune response against basal ganglia in the brain, induced by prior streptococcal infection. Chorea is a major criterion for the diagnosis of rheumatic fever and can also be the presenting feature of the disease. The incidence of rheumatic fever has been markedly decreased by improved socioeconomic conditions and increased antibiotic prescription. In the last two decades, however, this disease has reappeared and should be taken into account in the evaluation of children with movement disorders. In this paper, the author aims to present clinical, diagnostic and therapeutic findings of Sydenham's chorea patients.
西德纳姆舞蹈病是风湿热的神经学表现,是儿童期最常见的后天性舞蹈病。这种疾病继发于先前链球菌感染引发的针对大脑基底神经节的自身免疫反应。舞蹈病是风湿热诊断的主要标准,也可能是该疾病的首发特征。社会经济条件的改善和抗生素处方的增加使风湿热的发病率显著下降。然而,在过去二十年中,这种疾病再次出现,在评估有运动障碍的儿童时应予以考虑。在本文中,作者旨在介绍西德纳姆舞蹈病患者的临床、诊断和治疗结果。