Rhee Kyoung-Hoon, Lee Sang-Soo, Huh Joo-Ryung
Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
World J Gastroenterol. 2008 Apr 7;14(13):2115-7. doi: 10.3748/wjg.14.2115.
Castleman's disease (CD) of the pancreas/peripancreas is extremely rare. The recently introduced, endoscopic ultrasonography (EUS)-guided trucut biopsy (TCB) is a useful diagnostic modality for obtaining tissue samples from peripancreatic lesions. However, its role in diagnosing CD remains unknown. We report a case of localized, peripancreatic, hyaline-vascular CD biopsied using EUS. The pathology results were initially interpreted as an extranodal, marginal-zone B-cell lymphoma. However, polymerase chain reaction (PCR) study for the IgH gene rearrangement revealed a polyclonal pattern. We also reviewed the relevant literature. To our knowledge, this is the first illustrated report on EUS-TCB findings of CD with its pathology results of EUS-TCB mimicked a B-cell lymphoma.
胰腺/胰腺周围的卡斯尔曼病(CD)极为罕见。最近引入的内镜超声(EUS)引导下的 Trucut 活检(TCB)是从胰腺周围病变获取组织样本的一种有用的诊断方法。然而,其在诊断 CD 中的作用仍不明确。我们报告一例经 EUS 活检的局限性胰腺周围透明血管型 CD 病例。病理结果最初被解释为结外边缘区 B 细胞淋巴瘤。然而,IgH 基因重排的聚合酶链反应(PCR)研究显示为多克隆模式。我们还查阅了相关文献。据我们所知,这是第一份关于 CD 的 EUS-TCB 结果及其病理结果模仿 B 细胞淋巴瘤的图文报告。