Schmidt Lasse M, Foli-Andersen Nina J, Rasmussen Hans Morten Schnack, Wille-Jørgensen Peer A
Bispebjerg Hospital, Kirurgisk Afdeling K.
Ugeskr Laeger. 2008 Mar 10;170(11):947-51.
To assess Danish surgical departments' attitudes to and clinical guidelines on the use of perioperative thrombo-prophylaxis (TP).
Questionnaires regarding TP were sent to Danish departments which performed major surgery in 2005. The questionnaires contained questions regarding the use of TP routinely after clinical guidelines for both elective and acute surgery, indications for the use of TP, the type of TP and the duration of the TP treatment. The results are registered descriptively. The results are compared with five previously performed surveys from 1981-2000.
In the five surveys from 1981 to 2000, 85%, 90%, 92%, 95%, 93% answered the questionnaire, in the present survey 88% answered. Since the beginning of these surveys, there has been a significant increase in the use of TP following clinical guidelines from approximately 50% in 1981 to 96% of the departments performing major surgery in 2005. In acute surgery we found a significant increase in the number of departments using TP following clinical guidelines from 43% in 2000 to 81% in 2005 (p<0.01 Fishers exact test). All departments that used TP employed low molecular weight heparin. The use of prolonged TP was sporadic.
30 years after the first evidence in favour of TP was published, 96% of surgical departments which perform major surgery use TP routinely based on international clinical recommendations. A large number of departments use TP in connection with acute surgery in comparison with previous surveys. A future task is more focus on the use of prolonged TP after major surgical procedures.
评估丹麦外科科室对围手术期血栓预防(TP)使用的态度及临床指南。
向2005年进行大手术的丹麦科室发送关于TP的调查问卷。问卷包含有关按照择期和急性手术临床指南常规使用TP的问题、TP的使用指征、TP的类型以及TP治疗的持续时间。结果进行描述性记录。将结果与1981 - 2000年之前进行的五项调查进行比较。
在1981年至2000年的五项调查中,问卷回复率分别为85%、90%、92%、95%、93%,本次调查的回复率为88%。自这些调查开始以来,按照临床指南使用TP的情况有显著增加,从1981年的约50%增至2005年进行大手术科室的96%。在急性手术中,我们发现按照临床指南使用TP的科室数量显著增加,从2000年的43%增至2005年的81%(p<0.01,Fisher精确检验)。所有使用TP的科室均采用低分子量肝素。延长TP使用的情况较为零星。
在首个支持TP的证据发表30年后,96%进行大手术的外科科室根据国际临床建议常规使用TP。与之前的调查相比,大量科室在急性手术中使用TP。未来的任务是更加关注大手术术后延长TP的使用。