Mittnacht Alexander Jc, Fanshawe Michael, Konstadt Steven
Department of Anesthesiology, Mount Sinai Medical Center, New York, NY 10029, USA.
Semin Cardiothorac Vasc Anesth. 2008 Mar;12(1):33-59. doi: 10.1177/1089253208316442. Epub 2008 Apr 7.
Valvular heart disease can be an important finding in patients presenting for noncardiac surgery. Valvular heart disease and resulting comorbidity, such as heart failure or atrial fibrillation, significantly increase the risk for perioperative adverse events. Appropriate preoperative assessment, adequate perioperative monitoring, and early intervention, should hemodynamic disturbances occur, may help prevent adverse events and improve patient outcome. This review article aims to guide the practitioner in the various aspects of anesthetic management in the perioperative care of patients with valvular heart disease. The pharmacological approach to optimization of patient outcome with drugs, such as betablockers and lipid-lowering medications (statins), is an evolving field, and recent developments are discussed in this article.
心脏瓣膜病可能是接受非心脏手术患者的一项重要检查结果。心脏瓣膜病及其导致的合并症,如心力衰竭或心房颤动,会显著增加围手术期不良事件的风险。进行适当的术前评估、充分的围手术期监测,以及在出现血流动力学紊乱时进行早期干预,可能有助于预防不良事件并改善患者预后。这篇综述文章旨在指导从业者在心脏瓣膜病患者围手术期护理的麻醉管理各个方面。使用β受体阻滞剂和降脂药物(他汀类药物)等药物优化患者预后的药理学方法是一个不断发展的领域,本文将讨论其最新进展。