The challenge of HIV-1 subtype diversity.

作者信息

Taylor Barbara S, Sobieszczyk Magdalena E, McCutchan Francine E, Hammer Scott M

机构信息

Department of Medicine and the Division of Infectious Diseases, Columbia University Medical Center, New York 10032, USA.

出版信息

N Engl J Med. 2008 Apr 10;358(15):1590-602. doi: 10.1056/NEJMra0706737.

DOI:10.1056/NEJMra0706737

PMID:18403767

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2614444/

Abstract

摘要

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A nascent HIV type 1 epidemic among injecting drug users in Kabul, Afghanistan is dominated by complex AD recombinant strain, CRF35_AD.

AIDS Res Hum Retroviruses. 2007-6

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N Engl J Med. 2007-5-17

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Coreceptor tropism in human immunodeficiency virus type 1 subtype D: high prevalence of CXCR4 tropism and heterogeneous composition of viral populations.

J Virol. 2007-8

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Molecular epidemiology and prevalence of drug resistance-associated mutations in newly diagnosed HIV-1 patients in Portugal.

Infect Genet Evol. 2007-6

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HIV-1 subtype D infection is associated with faster disease progression than subtype A in spite of similar plasma HIV-1 loads.

J Infect Dis. 2007-4-15

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K65R development among subtype C HIV-1-infected patients in tenofovir DF clinical trials.

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Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry.

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The challenge of HIV-1 subtype diversity.

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