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拉克氏裂囊肿——一名小男孩头痛的罕见病因。

Rathke's cleft cyst--an uncommon cause of headache in a young boy.

作者信息

Sudhakar M K, Senthil N, Singh Mohini, Shantha Ghanshyam Palamaner Subash, Agarwal Gaurav, Vasugi O S M

机构信息

Department of General Medicine, Sri Ramachandra Medical College and Research Institute, Chennai.

出版信息

J Indian Med Assoc. 2007 Nov;105(11):648, 650, 656.

Abstract

Developmental disorders of the pituitary can present like a mass lesion in the region of the pituitary and produce pressure effects. Rathke's cleft cyst is one such developmental disorder of the pituitary which presents in early life producing pressure effects namely visual disturbances due to its proximity to optic chiasma, headache, and hormonal imbalance due to pituitary malfunction. In this case report a 19 years boy presented with symptoms of headache and gradual loss of vision over one year period. Neuro-imaging study demonstrated a cystic lesion in the region of the pituitary. Trans-sphenoidal hypophysectomy was performed. Histopathology of the biopsied material was suggestive of Rathke's cleft cyst. Following surgery the boy had a good visual recovery. So early diagnosis and removal of a Rathke's cleft cyst has a good prognosis as compared to a craniopharyngioma which is a very close differential diagnosis.

摘要

垂体发育障碍可表现为垂体区域的占位性病变并产生压迫效应。拉克氏囊肿就是这样一种垂体发育障碍,它在生命早期出现,产生压迫效应,即由于其靠近视交叉而导致视觉障碍、头痛,以及由于垂体功能异常导致的激素失衡。在本病例报告中,一名19岁男孩在一年时间里出现头痛和视力逐渐丧失的症状。神经影像学检查显示垂体区域有一个囊性病变。进行了经蝶窦垂体切除术。活检材料的组织病理学提示为拉克氏囊肿。手术后,该男孩视力恢复良好。因此,与颅咽管瘤(一种非常相近的鉴别诊断疾病)相比,早期诊断并切除拉克氏囊肿预后良好。

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