Le Elizabeth N, Gerstenblith Meg R, Gelber Allan C, Manno Rebecca L, Ranasinghe Padmini D, Sweren Ronald J, McGirt Laura Y
Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA.
J Am Acad Dermatol. 2008 Jul;59(1):148-51. doi: 10.1016/j.jaad.2008.03.010. Epub 2008 Apr 11.
Intravascular B-cell lymphoma is a rare type of non-Hodgkin's lymphoma that is characterized by a clonal proliferation of lymphoblasts within small blood vessels. Patients present with nonspecific symptoms and are often only given a diagnosis at autopsy. We report a case of intravascular B-cell lymphoma, characterized by pyrexia, anemia, thrombocytopenia, and mental status decline, without obvious cutaneous manifestations, that was diagnosed with blind skin biopsy.
血管内B细胞淋巴瘤是一种罕见的非霍奇金淋巴瘤，其特征是小血管内淋巴母细胞的克隆性增殖。患者表现为非特异性症状，通常仅在尸检时才得以诊断。我们报告一例血管内B细胞淋巴瘤病例，其特征为发热、贫血、血小板减少和精神状态下降，无明显皮肤表现，通过盲法皮肤活检得以确诊。
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