深静脉血栓形成和肺栓塞的抗凝治疗

Anticoagulant treatment of deep vein thrombosis and pulmonary embolism.

作者信息

Tran Huyen, McRae Simon, Ginsberg Jeffrey

机构信息

Department of Medicine, McMaster University Medical Centre, 1200 Main Street West, Room 3X28, Hamilton, Ontario L8N 3Z5, Canada.

出版信息

Cardiol Clin. 2008 May;26(2):235-50, vi-vii. doi: 10.1016/j.ccl.2007.12.006.

DOI:10.1016/j.ccl.2007.12.006

PMID:18406997

Abstract

Venous thrombosis is a common disease. As the mean age of the population increases, so does the incidence of venous thromboembolism. Anticoagulant therapy is equally effective in young and older patients, and can reduce substantially the associated morbidity and mortality. When considering long-term oral anticoagulant therapy in older patients, however, careful ongoing evaluation is imperative to ensure that the risk of bleeding does not outweigh the antithrombotic benefits.

摘要

静脉血栓形成是一种常见疾病。随着人口平均年龄的增长，静脉血栓栓塞的发病率也随之上升。抗凝治疗在年轻患者和老年患者中同样有效，并且可以大幅降低相关的发病率和死亡率。然而，在考虑对老年患者进行长期口服抗凝治疗时，必须进行仔细的持续评估，以确保出血风险不会超过抗血栓形成的益处。