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肥胖症患者的腹腔镜袖状胃切除术联合内镜引导

Laparoscopic sleeve gastrectomy with endoscopic guidance in morbid obesity.

作者信息

Frezza Eldo E, Barton Audrae, Herbert Haleigh, Wachtel Mitchell S

机构信息

Department of Surgery, Division of General Surgery, Texas Tech University Health Sciences Center, Lubbock, Texas 79415, USA.

出版信息

Surg Obes Relat Dis. 2008 Sep-Oct;4(5):575-9; discussion 580. doi: 10.1016/j.soard.2007.12.013. Epub 2008 Apr 14.

Abstract

BACKGROUND

Sleeve gastrectomy (SG) has been shown to be an effective first-stage procedure for morbidly obese patients. The SG is presently performed over a bougie of varying sizes, which is useful, but known to produce injuries on insertion. In a retrospective study, we evaluated the effect of the laparoscopic SG (LSG) on excess weight loss during 1 year of follow-up using a 29F endoscope instead of a bougie.

METHODS

During a 1-year period, LSG was performed on 20 (18 women and 2 men) consecutive patients. Gamma regression analysis was used to determine whether the variation in gender, age, initial body mass index, Hispanic ethnicity, and interval after surgery were related to excess weight loss.

RESULTS

No deaths and 1 minor complication of oozing from the staple line occurred. The excess weight loss increased steadily over time, with a median 20% at 3 months, 32% at 6 months, 42% at 9 months, and 53% at 12 months. The median initial body mass index was 44.5 kg/m2, and the median age was 50 years. Of the 20 patients, 2 were men (10%) and 18 women (90%); 5 (25%) were Hispanic and 15 (75%) were non-Hispanic. The patients had a median 11.5 co-morbidities. Nausea was common for about 7 days postoperatively. An increase in the initial body mass index and increased co-morbidities were the only 2 variables directly and statistically connected with the percentage of excess weight loss (P <.05).

CONCLUSION

The results of our study have shown that LSG with endoscopic guidance appears safe and effective and could be tried using a larger set of patients as a single-stage operation.

摘要

背景

袖状胃切除术(SG)已被证明是治疗病态肥胖患者的一种有效的一期手术。目前,SG手术是在不同尺寸的探条引导下进行的,这很有用,但已知在插入时会造成损伤。在一项回顾性研究中,我们评估了使用29F内窥镜而非探条进行腹腔镜袖状胃切除术(LSG)在1年随访期间对超重减轻的影响。

方法

在1年期间,对20例(18例女性和2例男性)连续患者进行了LSG手术。采用伽马回归分析来确定性别、年龄、初始体重指数、西班牙裔种族以及术后时间间隔的变化是否与超重减轻有关。

结果

无死亡病例,仅发生1例吻合口轻微渗血并发症。超重减轻随时间稳步增加,3个月时中位数为20%,6个月时为32%,9个月时为42%,12个月时为53%。初始体重指数中位数为44.5kg/m²,年龄中位数为50岁。20例患者中,2例为男性(10%),18例为女性(90%);5例(25%)为西班牙裔,15例(75%)为非西班牙裔。患者合并症中位数为11.5种。术后约7天恶心较为常见。初始体重指数增加和合并症增多是仅有的两个与超重减轻百分比直接且有统计学关联的变量(P<.05)。

结论

我们的研究结果表明,在内镜引导下的LSG似乎安全有效,可以尝试用于更多患者作为一期手术。

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