Wakelin D
Department of Zoology, University of Nottingham, England, U.K.
Parassitologia. 1991 Apr;33(1):61-6.
Effective control of parasitic zoonoses will ultimately require a combination of several approaches, including hygiene/sanitation, pasture management, chemotherapy and immunoprophylaxis. Development of vaccines, and other approaches to improving protective immunity, require a detailed understanding of parasite immunogenicity and host immune responsiveness. It is increasingly recognized that there is considerable variation in both of these parameters, and that this variation is genetically determined. Recent studies in this area and the consequences for control are discussed.
有效控制寄生性人畜共患病最终需要多种方法相结合，包括卫生/环境卫生、牧场管理、化学疗法和免疫预防。疫苗的研发以及其他改善保护性免疫的方法需要详细了解寄生虫的免疫原性和宿主的免疫反应性。人们越来越认识到这两个参数都存在相当大的差异，而且这种差异是由基因决定的。本文讨论了该领域的最新研究及其对疾病控制的影响。
