基于氮杂环卡宾的镍（II）配合物催化的未活化芳基氯的室温 Kumada 交叉偶联反应
Room-temperature Kumada cross-coupling of unactivated aryl chlorides catalyzed by N-heterocylic carbene-based nickel(II) complexes.
作者信息
Xi Zhenxing, Liu Bin, Chen Wanzhi
机构信息
Department of Chemistry, Zhejiang University, Xixi Campus, Hangzhou, PR China.
出版信息
J Org Chem. 2008 May 16;73(10):3954-7. doi: 10.1021/jo800197u. Epub 2008 Apr 16.
PMID:18412386
Abstract
The Kumada cross-coupling reaction of a variety of unactivated aryl chlorides, vinyl chlorides, and heteroaryl chlorides catalyzed by nickel(II) complexes containing pyridine-functionalized NHC ligands is described. The catalysts are so active that the reactions proceed at room temperature in excellent yields.
摘要
本文描述了由含吡啶官能化NHC配体的镍（II）配合物催化的各种未活化芳基氯、氯乙烯和杂芳基氯的 Kumada 交叉偶联反应。这些催化剂活性极高，反应在室温下即可进行，产率优异。
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