Mutschler J, Diehl A, Kiefer F
Klinik für Abhängiges Verhalten und Suchtmedizin, Zentralinstitut für Seelische Gesundheit, Mannheim.
Fortschr Neurol Psychiatr. 2008 Apr;76(4):225-31. doi: 10.1055/s-2007-1016438.
Recently, we have been observing an increase in prescription of Disulfiram requiring medical knowledge concerning the overall effects, side effects and drug interactions of this substance. In the following report, we give an overview about the pharmacology and the side effects of Disulfiram. As an example we demonstrate a case, in which an acute neurological deficit was misjudged as a side effect of Disulfiram. Furthermore, the potential of Disulfiram as a promising treatment in addiction medicine will be discussed.
最近,我们注意到双硫仑的处方量有所增加,这需要了解该物质的总体作用、副作用及药物相互作用等医学知识。在以下报告中,我们将概述双硫仑的药理学及副作用。我们将举例说明一个病例,其中急性神经功能缺损曾被误诊为双硫仑的副作用。此外,还将讨论双硫仑在成瘾医学中作为一种有前景的治疗方法的潜力。