The tail of mycolic acids.
作者信息
Lu Jeff Zhiqiang, Prigge Sean T
机构信息
Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA.
出版信息
Chem Biol. 2008 Apr;15(4):309-10. doi: 10.1016/j.chembiol.2008.04.001.
Abstract
The FabH enzyme from M. tuberculosis binds the acyl tail of large substrates at the end of a buried hydrophobic tunnel. Sachdeva et al. (2008) use reactive chemical probes and X-ray crystallography to show that substrates can bind to an open state of FabH without threading through the tunnel.
摘要
Zotero 插件