Okada Junna, Moroi Yoichi, Tsujita Jun, Takahara Masakazu, Urabe Kazunori, Kiryu Hiromaro, Furue Masutaka
Kyushu University Graduate School of Medicine, Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maedashi 3-1-1, Higashi-ku, 812-8582 Fukuoka, Japan.
Eur J Dermatol. 2008 Mar-Apr;18(2):185-7. doi: 10.1684/ejd.2008.0358.
We report the case of a 26-year-old man who presented with small soft nodules with tiny hairs that had been present on his nose since childhood. The nodules were initially diagnosed as melanocytic nevi. However, dermoscopy showed many uniform hair follicles and an interfollicular 'pseudo-pigment network' in the nodules. Histologically, many well-differentiated hair follicles and sebaceous glands were seen in the dermis. Serial sectioning revealed neither central cysts nor a central canal. We therefore diagnosed this case as hair follicle nevus. Dermoscopy is now widely used as a non-invasive, in vivo technique for the diagnosis of pigmented skin lesions. Hair follicle nevus is a very rare disease and this is the first report to demonstrate the manifestation of this clinical entity by dermoscopy.
我们报告了一例26岁男性患者的病例,其自童年起鼻子上就有带有细小毛发的小软结节。这些结节最初被诊断为黑素细胞痣。然而,皮肤镜检查显示结节内有许多均匀的毛囊和毛囊间的“假色素网络”。组织学上,真皮内可见许多分化良好的毛囊和皮脂腺。连续切片未发现中央囊肿或中央管。因此,我们将该病例诊断为毛囊痣。皮肤镜检查目前作为一种非侵入性的活体技术,广泛应用于色素性皮肤病变的诊断。毛囊痣是一种非常罕见的疾病,这是第一份通过皮肤镜检查展示该临床实体表现的报告。