Santana Genoile Oliveira, Souza Lorena Rocha, Azevedo Matheus, Sá Ana Carolina, Bastos Clara Maia, Lyra André Castro
Gastrohepatology Unit, Federal University of Bahia, Bahia, Brazil.
Arq Gastroenterol. 2008 Jan-Mar;45(1):64-8. doi: 10.1590/s0004-28032008000100012.
Crohn's disease is a chronic inflammatory disorder with diversity on its clinical presentation that may be observed from the varying age of onset of symptoms to the site of occurrence of the illness. There is a need for a replicable and uniform description of the disease allowing a comparison between distinct study populations. The 1998 Vienna classification characterizes patients according to three clinical aspects: age at diagnosis, location and disease behavior.
To describe Crohn's disease in patients from a reference center of Salvador, BA, Brazil according to the Vienna classification.
Between January and October of 2005, patients (n = 47) having at least one endoscopic and radiological examination of the intestine participated in this study.
Most of the participants had the diagnosis of the disease when they were younger than 40 years old (70.2%) while an ileocolic location (38.3%) and the penetrating form (46.8%) were the most prevalent clinical presentation. The restricted location of the ileum (L1) was more frequent in nonstricturing, nonpenetrating disease (B1) while the ileocolic disease (L3) was more associated with the penetrating behavior (B3).
In this study, differently from the first description of the Vienna classification, the large number of patients presenting a complicated stage of the disease can be attributed to the fact that it was carried out at a reference center, where many patients present with the disease at an advanced stage.
克罗恩病是一种临床表现多样的慢性炎症性疾病,从症状出现的不同年龄到疾病发生部位均可观察到这种多样性。需要对该疾病进行可重复且统一的描述,以便在不同研究人群之间进行比较。1998年维也纳分类根据三个临床方面对患者进行特征描述:诊断时的年龄、病变部位和疾病行为。
根据维也纳分类描述巴西巴伊亚州萨尔瓦多一家参考中心的克罗恩病患者情况。
2005年1月至10月期间,至少接受过一次肠道内镜和放射学检查的患者(n = 47)参与了本研究。
大多数参与者在40岁之前被诊断出患有该疾病(70.2%),而回结肠部位(38.3%)和穿透型(46.8%)是最常见的临床表现。在非狭窄、非穿透性疾病(B1)中,回肠局限性病变(L1)更为常见,而回结肠疾病(L3)与穿透性行为(B3)的关联更为密切。
在本研究中,与维也纳分类的首次描述不同,出现疾病复杂阶段的患者数量较多可归因于该研究是在一家参考中心进行的,许多患者在疾病晚期才前来就诊。