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挪威糖尿病足溃疡的病史及相关因素:北特伦德拉格健康研究

History of and factors associated with diabetic foot ulcers in Norway: the Nord-Trøndelag Health Study.

作者信息

Iversen Marjolein M, Midthjell Kristian, Østbye Truls, Tell Grethe S, Clipp Elizabeth, Sloane Richard, Nortvedt Monica W, Uhlving Sverre, Hanestad Berit R

机构信息

Faculty of Health and Social Sciences, Bergen University College, Bergen, Norway.

出版信息

Scand J Public Health. 2008 Jan;36(1):62-8. doi: 10.1177/1403494807085314.

Abstract

AIMS

To determine the proportion of people with diabetes mellitus reporting a history of foot ulcer and to investigate factors associated with this adverse outcome.

METHODS

All inhabitants aged 20 years and older residing in a large geographic region were invited to participate in the Nord-Trøndelag Health Study, 71% (n=65,604) attended. Those reporting diabetes (n=1,972) were invited to take part in an ancillary study on diabetes. Based on 1,494 responses to the question: "Have you had a foot ulcer that required more than three weeks to heal'', the proportion with a history of foot ulcer was estimated.

RESULTS

The overall proportion with a history of foot ulcer was 10.4% (95% CI 8.8-11.9%). In the final multivariate logistic regression model, significant factors for a foot ulcer history included age > or =75 years (OR 1.8, 95% CI 1.2-2.8), height (men>175 cm, women>161 cm) (1.9, 95% CI 1.3-2.8), gender (male) (1.5, 95% CI 1.03-2.2), using insulin (1.6, 95% CI 1.1-2.4), and macrovascular complications (1.8, 95% CI 1.2-2.6).

CONCLUSIONS

The proportion of people reporting a history of foot ulcer in this population-based study exceeded the proportion of foot ulcer history reported previously. Height as a correlate has been occasionally reported in previous studies and needs further attention. Associated factors for a foot ulcer history help identify individuals who may be at particular risk of this adverse outcome.

摘要

目的

确定报告有足部溃疡病史的糖尿病患者比例,并调查与这一不良结局相关的因素。

方法

邀请居住在一个大地理区域内所有20岁及以上的居民参加北特伦德拉格健康研究,71%(n = 65,604)的人参加了。那些报告患有糖尿病的人(n = 1,972)被邀请参加一项糖尿病辅助研究。基于对“您是否有过需要超过三周才能愈合的足部溃疡”这一问题的1,494份回复,估算有足部溃疡病史的比例。

结果

有足部溃疡病史的总体比例为10.4%(95%置信区间8.8 - 11.9%)。在最终的多变量逻辑回归模型中,有足部溃疡病史的显著因素包括年龄≥75岁(比值比1.8,95%置信区间1.2 - 2.8)、身高(男性>175厘米,女性>161厘米)(1.9,95%置信区间1.3 - 2.8)、性别(男性)(1.5,95%置信区间1.03 - 2.2)、使用胰岛素(1.6,95%置信区间1.1 - 2.4)以及大血管并发症(1.8,95%置信区间1.2 - 2.6)。

结论

在这项基于人群的研究中,报告有足部溃疡病史的人群比例超过了先前报告的足部溃疡病史比例。身高作为一个相关因素在先前研究中偶尔有报告,需要进一步关注。有足部溃疡病史的相关因素有助于识别可能面临这一不良结局特定风险的个体。

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