[Contemporary concept of placebo usage in clinical trials of new drugs].

The placebo-controlled trials have been almost always controversial since the beginning of introduction of this method into new pharmacotherapy investigations. From the legal and ethical point of view the usage of placebo is more and more frequently criticized because it devoids the patients of standard therapy advantages. Therefore, contemporary tendency to solve of ethical placebo problem connected with clinical trials of new drugs is often--application of more safe methods of results objectifying in new therapy by comparison of the results of clinical trials in the group taking a new drug to be tested to the one treated by conventional, standard, established the best so far known, pharmacotherapy.