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腹腔镜下切除奥斯勒-韦伯-伦杜病变。

Laparoscopic resection of Osler-Weber-Rendu lesion.

作者信息

Park John, Ellis Bryan, Juergens Christopher

机构信息

Department of Surgery, Good Samaritan Hospital, Cincinnati, Ohio 45220, USA.

出版信息

JSLS. 2008 Apr-Jun;12(2):180-2.

Abstract

BACKGROUND AND OBJECTIVES

Osler-Weber-Rendu is a hereditary disease characterized by telangiectasias, arteriovenous malformations, and aneurysms involving the cutaneous, gastrointestinal, pulmonary, and central nervous systems. This report describes a combinatorial approach using laparoscopic and intraoperative endoscopy to perform a partial gastric resection of bleeding arteriovenous malformations.

METHODS

A 70-year-old female with a history of bleeding from Osler-Weber-Rendu disease presented to the emergency department complaining of hematemesis. Her vital signs were unstable, and she was immediately resuscitated with intravenous fluids and transfusions. A combined laparoscopic and intraoperative endoscopic approach to a partial gastric resection was planned. Intraoperatively, a single lesion was identified along the posterior aspect of the greater curvature of the stomach by using endoscopy. The blood supply was taken down with a Ligasure and gastric resection with a 60-mm Echelon stapler.

RESULTS

The pathology report confirmed the complete resection of the arteriovenous malformations. The patient recovered well and was discharged home several days later without any pain complaints.

CONCLUSIONS

Little has been written about the medical treatment of Osler-Weber-Rendu arteriovenous malformations, let alone surgical treatment. A combinatorial laparoscopic and intraoperative endoscopic approach to gastric resection allows both minimization of the gastric resection and the complete identification and removal of the arteriovenous malformations.

摘要

背景与目的

遗传性出血性毛细血管扩张症(Osler-Weber-Rendu病)是一种遗传性疾病,其特征为毛细血管扩张、动静脉畸形和动脉瘤,累及皮肤、胃肠道、肺和中枢神经系统。本报告描述了一种联合使用腹腔镜和术中内镜进行出血性动静脉畸形部分胃切除术的方法。

方法

一名有遗传性出血性毛细血管扩张症出血史的70岁女性因呕血就诊于急诊科。她的生命体征不稳定,立即通过静脉输液和输血进行复苏。计划采用腹腔镜和术中内镜联合进行部分胃切除术。术中,通过内镜在胃大弯后侧发现一个单一病变。使用结扎速血管闭合系统切断血供,并用60毫米的Echelon吻合器进行胃切除。

结果

病理报告证实动静脉畸形已完全切除。患者恢复良好,几天后出院,无任何疼痛主诉。

结论

关于遗传性出血性毛细血管扩张症动静脉畸形的药物治疗,相关文献较少,更不用说手术治疗了。联合腹腔镜和术中内镜进行胃切除术,既能使胃切除范围最小化,又能完整识别并切除动静脉畸形。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4a2/3016177/1f3b827aab7a/jsls-12-2-180-g01.jpg

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