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一名慢性乙型肝炎患者术前被诊断为肝细胞癌的肝内脾组织植入:病例报告

Hepatic splenosis preoperatively diagnosed as hepatocellular carcinoma in a patient with chronic hepatitis B: a case report.

作者信息

Choi Gi-Hong, Ju Man-Ki, Kim June-Young, Kang Chang-Moo, Kim Kyung-Sik, Choi Jin-Sub, Han Kwang-Hyub, Park Mi-Suk, Park Young-Nyun, Lee Woo-Jung, Kim Byong-Ro

机构信息

Department of Surgery, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul, Korea.

出版信息

J Korean Med Sci. 2008 Apr;23(2):336-41. doi: 10.3346/jkms.2008.23.2.336.

Abstract

We report on a case of hepatic splenosis. A 32-yr-old man underwent a splenectomy due to trauma at the age of 6. He had been diagnosed as being a chronic hepatitis B-virus carrier 16 yr prior to the surgery. The dynamic computer tomography (CT) performed due to elevated serum alpha-fetoprotein (128 ng/mL) demonstrated two hepatic nodules, which were located near the liver capsule. A nodule in Segment IVa had a slight enhancement during both the arterial and portal phases, and another nodule in Segment VI showed a slight enhancement only in the portal phases. Dynamic magnetic resonance imaging (MRI) of the mass in Segment VI showed enhanced development in the arterial phases and slight hyperintensivity to the liver parenchyma in the portal phases. These imaging findings suggested a hypervascular tumor in the liver, which could be either focal nodular hyperplasia, adenoma, or hepatocellular carcinoma (HCC). Even though these lesions were diagnosed as HCC, some of the findings were not compatible with typical HCC. On dynamic CT and MRI, all lesions showed a slight arterial enhancement and did not show early venous washout. All lesions were located near the liver capsule. These findings, along with a history of splenectomy, suggested a diagnosis of hepatic splenosis.

摘要

我们报告一例肝脾组织异位病例。一名32岁男性在6岁时因外伤接受了脾切除术。手术前16年,他被诊断为慢性乙型肝炎病毒携带者。因血清甲胎蛋白升高(128 ng/mL)进行的动态计算机断层扫描(CT)显示肝脏有两个结节,位于肝包膜附近。IVa段的一个结节在动脉期和门静脉期均有轻度强化,VI段的另一个结节仅在门静脉期有轻度强化。VI段肿块的动态磁共振成像(MRI)显示动脉期强化明显,门静脉期相对于肝实质呈轻度高信号。这些影像学表现提示肝脏存在高血供肿瘤,可能是局灶性结节性增生、腺瘤或肝细胞癌(HCC)。尽管这些病变被诊断为HCC,但部分表现与典型HCC不符。在动态CT和MRI上,所有病变均表现为轻度动脉期强化,未出现早期静脉期廓清。所有病变均位于肝包膜附近。这些表现,结合脾切除术病史,提示诊断为肝脾组织异位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad4d/2526445/c2d18ac7cfa8/jkms-23-336-g001.jpg

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