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[形态学磁共振成像:其在神经退行性疾病诊断中的价值]

[Morphological magnetic resonance imaging: its value for the diagnosis of neurodegenerative diseases].

作者信息

Hahn U, Schwarz J, Gratz S, Kaiser J W, Jarnig M, Förstl H

机构信息

Praxis für Radiologische Diagnostik und Nuklearmedizin, Stuttgart Bad Cannstatt.

出版信息

Dtsch Med Wochenschr. 2008 May;133 Suppl 1:S15-8. doi: 10.1055/s-2008-1075681.

Abstract

Magnetic resonance imaging (MRI) plays an important role in differentiating idiopathic Parkinson's disease (PD) from its atypical forms. Causes like chronic vascular disease and normal-pressure hydrocephalus are easily visualized. Furthermore, specific atrophy patterns can be found with multi-system atrophies, corticobasal degeneration and progressive supranuclear palsy. In addition the review also deals with specific imaging criteria of other neurodegenerative disorders, such as Wilson's disease, neurodegeneration with iron accumulation in the brain and Huntington's chorea. MRI is of minor importance for differentiating Alzheimer's disease from frontotemporal dementia or dementia with Lewy bodies. However, specific patterns are found in cerebral amyloid angiopathy and prion diseases..

摘要

磁共振成像(MRI)在区分特发性帕金森病(PD)与其非典型形式方面发挥着重要作用。慢性血管疾病和正常压力脑积水等病因很容易被观察到。此外,多系统萎缩、皮质基底节变性和进行性核上性麻痹可发现特定的萎缩模式。此外,该综述还涉及其他神经退行性疾病的特定成像标准,如威尔逊病、脑铁沉积神经变性和亨廷顿舞蹈病。MRI在区分阿尔茨海默病与额颞叶痴呆或路易体痴呆方面重要性较低。然而,在脑淀粉样血管病和朊病毒病中可发现特定模式。

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