Gottlieb Klaus, Lin Paul H, Liu David M, Anders Karl
Endoscopic Ultrasound and Interventional Endoscopy, 1314 S Grand Blvd #2141, Spokane, WA 99202, United States.
World J Gastroenterol. 2008 Apr 28;14(16):2586-9. doi: 10.3748/wjg.14.2586.
Chordomas are rare tumors which originate from the remnants of the notochord. These tumors are locally aggressive and have a predilection for the ends of the axial skeleton. An important prerequisite for optimal management of these tumors is a correct preoperative diagnosis. The present case is the first report of the use of endoscopic ultrasound to obtain transrectal fine needle aspiration biopsy of a presacral chordoma. A review of the prior computer tomography (CT) scans allowed us to calculate the tumor volume doubling time (18.3 mo). Transrectal biopsy of chordomas is controversial, however we believe that such concerns are not justified.
脊索瘤是起源于脊索残余组织的罕见肿瘤。这些肿瘤具有局部侵袭性,且好发于中轴骨骼的末端。对这些肿瘤进行最佳治疗的一个重要前提是术前做出正确诊断。本病例是首例使用超声内镜经直肠对骶前脊索瘤进行细针穿刺活检的报告。回顾之前的计算机断层扫描(CT)扫描结果,我们得以计算出肿瘤体积倍增时间(18.3个月)。经直肠对脊索瘤进行活检存在争议,然而我们认为这些担忧是没有道理的。