Lanitis Sophocles, Filippakis George, Al Mufti Ragheed, Hadjiminas Dimitri J
Breast Care Unit, St Mary's NHS Trust, London, UK.
J Med Case Rep. 2008 Apr 28;2:126. doi: 10.1186/1752-1947-2-126.
Breast cancer in men is rare. The evidence about treatment has been derived from data on the management of the disease in women. The usual treatment is for male patients to undergo modified radical mastectomy. There is insufficient experience of breast conserving surgery with preservation of the nipple. The management of patients who demand such an approach for personal reasons remains a challenge for both the surgeon and oncologist.
A 50-year-old man with a breast cancer was successfully managed with breast conserving surgery with nipple preservation combined with axillary clearance and postoperative radiotherapy, chemotherapy and hormone treatment. Since there are no similar cases in the literature, we discuss the feasibility, safety and possible indications of such an approach.
Despite the limited indications and evidence about the safety and efficacy of breast conserving surgery with nipple preservation in men with breast cancer, it is a feasible approach if other options are declined by the patient. More studies are necessary to reach firm conclusions about the safety of such an approach.
男性乳腺癌较为罕见。关于其治疗的证据来自女性乳腺癌治疗的数据。男性患者的常规治疗是接受改良根治性乳房切除术。保留乳头的保乳手术经验不足。对于因个人原因要求采用这种方法的患者的管理,对外科医生和肿瘤学家来说仍然是一个挑战。
一名50岁男性乳腺癌患者通过保留乳头的保乳手术联合腋窝清扫及术后放疗、化疗和激素治疗成功治愈。由于文献中没有类似病例,我们讨论了这种方法的可行性、安全性及可能的适应证。
尽管保留乳头的保乳手术在男性乳腺癌患者中的安全性和有效性的适应证有限且证据不足,但如果患者拒绝其他选择,这是一种可行的方法。需要更多研究才能就这种方法的安全性得出确凿结论。