采用VOCAL方法通过三维超声评估卵黄囊体积。

Yolk sac volume assessed by three-dimensional ultrasonography using the VOCAL method.

作者信息

Rôlo Líliam Cristine, Nardozza Luciano Marcondes Machado, Araujo Júnior Edward, Nowak Paulo Martin, Moron Antonio Fernandes

机构信息

Department of Obstetrics, São Paulo Federal University (UNIFESP - EPM), São Paulo, SP, Brazil.

出版信息

Acta Obstet Gynecol Scand. 2008;87(5):499-502. doi: 10.1080/00016340802011595.

DOI:10.1080/00016340802011595

PMID:18446531

Abstract

OBJECTIVES

Establish normative data for yolk sac volume (YSV) at 7-10 weeks of gestation assessed by transvaginal three-dimensional ultrasonography (3D-US) using the VOCAL method and analyze its correlation with gestational age (GA) and crown-rump length (CRL).

METHODS

A cross-sectional study involving 62 normal pregnancies was performed to assess YSV from 7 to 10 weeks of gestational age. An endocavitary volumetric transducer (3D5-8EK) was used for all measurements. The VOCAL (Virtual Organ Computer-aided AnaLysis) method with a 30 degrees rotation angle was used for volumetric calculations. Regression models were constructed to analyze the correlation between YSV and GA or CRL The mean, standard deviation, median, minimum and maximum values were calculated for each gestational age.

RESULTS

There was a poor correlation between YSV and GA or CRL. The quadratic regression was the model that best expressed the correlation between these variables: R2=0.188 for GA and R2=0.203 for CRL. The mean YSV went from 0.063 cm(3) (95% CI: 0.047; 0.080) at 7 weeks to 0.164 cm3 (95% CI 0.095; 0.232) at 10 weeks.

CONCLUSION

Reference limits were generated for first trimester YSV using 3D-US. There was a poor correlation between YSV and GA or CRL.

摘要

目的

采用容积对比成像（VOCAL）法，通过经阴道三维超声（3D-US）建立妊娠7至10周时卵黄囊体积（YSV）的规范数据，并分析其与孕周（GA）和头臀长（CRL）的相关性。

方法

进行一项横断面研究，纳入62例正常妊娠，评估妊娠7至10周时的YSV。所有测量均使用腔内容积探头（3D5-8EK）。采用旋转角度为30度的VOCAL（虚拟器官计算机辅助分析）法进行容积计算。构建回归模型以分析YSV与GA或CRL之间的相关性。计算每个孕周的均值、标准差、中位数、最小值和最大值。

结果

YSV与GA或CRL之间的相关性较差。二次回归是最能表达这些变量之间相关性的模型：与GA的R2 = 0.188，与CRL的R2 = 0.203。YSV的均值从7周时的0.063 cm³（95% CI：0.047；0. .080）增加到10周时的0.164 cm³（95% CI 0.095；0.232）。