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印度南部伤寒热病原体的流行病学转变、季节变化及抗菌药物敏感性模式

Epidemiological shift, seasonal variation and antimicrobial susceptibility patterns among enteric fever pathogens in South India.

作者信息

Vidyalakshmi K, Yashavanth R, Chakrapani M, Shrikala B, Bharathi B, Suchitra U, Dhanashree B, Dominic R M S

机构信息

Department of Microbiology, Kasturba Medical College, Mangalore 575001, Karnataka, India.

出版信息

Trop Doct. 2008 Apr;38(2):89-91. doi: 10.1258/td.2007.070271.

DOI:10.1258/td.2007.070271
PMID:18453495
Abstract

Between January 2005 and December 2006, a higher incidence of paratyphoid fever (53.8%) compared to typhoid fever (44.9%) has been observed at a tertiary hospital in South India. A definite seasonal pattern of incidence is seen in paratyphoid fever (peak incidence during October-December, i.e., post monsoon period) but not in typhoid fever. Decreased fluoroquinolone susceptibility is much higher in S. Paratyphi A (98.8%) as compared to S. Typhi (46.5%). These findings are of importance in therapeutic decision making, development of vaccination strategies and implementing public health measures for disease control.

摘要

2005年1月至2006年12月期间,印度南部一家三级医院观察到,副伤寒热的发病率(53.8%)高于伤寒热(44.9%)。副伤寒热呈现出明确的发病季节性模式(10月至12月发病率最高,即季风期过后),而伤寒热则没有。甲型副伤寒沙门菌对氟喹诺酮的敏感性降低(98.8%),远高于伤寒沙门菌(46.5%)。这些发现对于治疗决策、疫苗接种策略的制定以及实施疾病控制的公共卫生措施具有重要意义。

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