Rastegaeva L I, Morozov I A, Zagrebin A M
Arkh Anat Gistol Embriol. 1991 Sep-Oct;101(9-10):75-80.
The time, when the first villi appear, is defined. Quantitative composition, percent content, height of the villi of the mucous membrane in all parts of the small intestine during various periods of the intrauterine development are presented. In 17-week-old embryos at the level of the duodenum the first villi are noted and their formation in the middle part of the intestinal tube is revealed. By the 8th-9th weeks of development they appear at the level of the caudal part of the intestine. This demonstrates asynchronism of their formation in the cranio-caudal direction. The periods of their intensive growth in height in the first part of the intestine correspond to 8-10, 12-16, 24 weeks of the fetus age, in the second part--to 8-10, 18-20 weeks, in the third--to 10-12, 16-18, 26-28 weeks. These periods alternate with an abatement in growth intensity, which is connected with an increasing width of the villi themselves, with amount of newly formed villi and with changes of the intestinal tube diameter. The form of the villi is rather variable.
首次出现绒毛的时间已明确。文中呈现了子宫内发育各阶段小肠各部位黏膜绒毛的定量组成、百分比含量及高度。在17周龄胚胎的十二指肠水平可观察到首批绒毛，并发现其在肠管中部形成。到发育第8 - 9周时，它们出现在肠尾端水平。这表明绒毛在头 - 尾方向形成的异步性。小肠第一部分绒毛高度快速增长期分别对应胎儿8 - 10周、12 - 16周、24周；第二部分对应8 - 10周、18 - 20周；第三部分对应10 - 12周、16 - 18周、26 - 28周。这些时期与生长强度减弱交替出现，这与绒毛自身宽度增加、新形成绒毛数量以及肠管直径变化有关。绒毛的形态变化较大。
